Research that reaches home.
For thirty years, Hamilton Medical Research Group has brought Phase II–IV clinical trials from the world’s leading pharmaceutical companies to patients in their own community.
Clinical trials begin in laboratories and boardrooms around the world. None of it matters until research reaches a patient.
Hamilton Medical Research Group is that last mile — six practicing physicians, a nurse practitioner, and a dedicated clinical operations team conducting Phase II–IV trials from one site in Hamilton, Ontario.
Led by founder Dr. Richard Tytus, our investigators recruit from their own active family practices, giving sponsors a direct line to rapid, representative enrollment. Every trial is run to GCP, Health Canada, and FDA standards.
The siteVictoria Medical Centre, 304 Victoria Ave N
Investigator-led.
Sponsor-trusted.
HMRG partners with pharmaceutical sponsors and contract research organizations on Phase II–IV trials, managing the full site-level lifecycle — regulatory submissions, ethics applications, recruitment, clinical assessments, investigational product management, and close-out reconciliation. One team carries the protocol from feasibility to final query.
New medicine,
familiar faces.
Most HMRG investigators are practicing family physicians — for many participants, the doctor running their study is one they already know. Every trial is reviewed by Health Canada and an independent ethics board, and explained in plain language before you decide anything.
Participation is voluntary and costs you nothing. Many studies also compensate you for time and travel.
Read the patient FAQ“To study the phenomena of disease without books is to sail an uncharted sea, while to study books without patients is not to go to sea at all.”
Areas of Focus
Eight therapeutic areas anchored in primary care — where chronic disease is diagnosed, managed, and best studied.
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Cardiovascular
Lipid disorders, hypertension, and cardiovascular risk reduction trials with sponsors including Amgen.
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Diabetes & Metabolic
Type 2 diabetes management, insulin therapies, and metabolic disease trials with Novo Nordisk and Eli Lilly.
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Obesity & Weight
GLP-1 receptor agonist studies and oral weight-loss therapies for patients with cardiometabolic comorbidities.
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Respiratory
Chronic cough and airway studies in partnership with GSK/Bellus Health.
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Renal
Kidney disease and renal outcomes studies with Roche/Regeneron.
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Vaccines
Immunization trials including mRNA and RSV vaccine studies with Moderna and Pfizer.
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Women’s Health
Studies in conditions that affect women, including polycystic ovary syndrome (PCOS) and urinary incontinence.
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General Medicine
Primary-care research rooted in our investigators’ active family practices and one of Canada’s most diverse patient populations.
Start a conversation
Sponsors and CROs — request feasibility information or a site visit. Patients — ask about current and upcoming studies. Every message goes to our clinical operations team.






